Principal Clinical Scientist

Principal Clinical Scientist (AI Training) About The Role What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring the clinical data powering next-generation AI systems meets the standards that matter in the real world.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory standards
• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data and outcomes
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong grounding in clinical research methodology, biostatistics, translational science, or related disciplines
• Sharp eye for scientific accuracy, regulatory alignment, and data quality
• Self-directed and comfortable delivering high-quality work independently

Nice to Have

• Prior experience with data annotation, data quality assurance, or AI evaluation workflows
• Background in pharmacovigilance, outcomes research, or clinical evidence synthesis
• Familiarity with AI tools or clinical informatics platforms

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Fully remote and flexible — contribute on a schedule that fits your life
• Freelance autonomy: set your own pace, work from anywhere, collaborate globally
• Make a tangible impact on how AI understands and evaluates real-world clinical evidence
• Potential for ongoing work and contract extension as new projects launch