Principal Clinical Scientist

Principal Clinical Scientist (AI Training) About The Role What if your years of clinical trial expertise could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring the clinical data that trains and evaluates next-generation AI systems meets the standards expected in real regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the cutting edge of biomedical AI without leaving their domain behind.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes
• Help establish the scientific standards that frontier AI systems use to understand real-world clinical evidence

Who You Are

• Senior clinical scientist with deep, hands-on experience designing clinical trial protocols for regulatory submission
• Expert in interpreting clinical data for major regulatory agencies — FDA, EMA, or equivalent
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Detail-oriented and systematic — you hold data to a high standard and can articulate exactly why
• Comfortable working independently in an asynchronous, remote environment

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation systems
• Familiarity with AI tools or clinical informatics platforms
• Background in drug development, medical devices, or digital health research
• Experience bridging clinical and technical teams across complex research workflows

Why Join Us

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale
• Fully remote and flexible — work on your own schedule, from anywhere
• Freelance autonomy with meaningful, expert-level work that matches your seniority
• Collaborate with leading AI research labs and teams on genuinely novel problems
• Potential for ongoing work and contract extension as projects evolve