Associate Medical Director

Associate Medical Director – Site Network (UK)

60% Principal Investigator (PI) Work / 40% Operations &​ Site Growth

Role Overview

We are seeking a clinically active Associate Medical Director to join a growing UK clinical site network. This hybrid role combines hands-on Principal Investigator (PI) leadership (60%) with strategic operational and site expansion responsibilities (40%) .

You will play a key role in driving high-quality clinical trial delivery , ensuring patient safety, scientific integrity, and regulatory compliance , while also supporting the growth, performance, and scalability of the site network across the UK .

Key Responsibilities

Principal Investigator / Clinical Delivery (60%)

• Act as Principal Investigator (PI) on assigned interventional clinical trials across multiple therapeutic areas (with emphasis on oncology, haematology, and complex chronic disease studies where applicable)
• Ensure full compliance with

ICH-GCP, UK regulatory requirements, and study protocols

• Oversee patient eligibility, informed consent, safety oversight, and medical decision-making
• Provide

medical leadership on protocol feasibility, amendments, and study conduct

• Lead investigator oversight visits, sponsor interactions, and audit/inspection readiness
• Support and mentor sub-investigators and site clinicians to maintain high-quality delivery

Site Operations &​ Growth (40%)

• Support expansion of the UK site network footprint , including identification of new site opportunities
• Contribute to

site start-up strategy , feasibility assessments, and pipeline prioritisation

• Work closely with operations teams to improve recruitment performance, activation timelines, and retention
• Build and maintain relationships with

sponsors, CROs, and strategic partners

• Support development of standardised processes across sites to improve efficiency and quality
• Provide clinical input into

business development proposals and feasibility pipelines

• Help shape the medical and operational strategy of the network

Key Requirements

• GMC-registered physician with active licence to practise in the UK
• Strong background in

clinical trials (industry or academic setting)

• Prior experience as Principal Investigator (PI) or Sub-Investigator
• Solid understanding of

ICH-GCP, MHRA expectations, and clinical research governance

• Demonstrated ability to balance clinical responsibility with operational leadership
• Excellent communication skills with ability to engage investigators, sponsors, and internal teams
• Strong organisational and decision-making capability in fast-paced environments

What This Role Offers

• Hybrid role combining hands-on patient-facing PI work with strategic leadership
• Opportunity to shape and scale a

rapidly growing UK site network

• Direct impact on trial delivery performance and patient access to innovation
• High visibility role with influence across

clinical operations and business growth

• Collaborative environment with strong focus on quality and scientific integrity